The great open sky of imagination: for those who u Fermented Foods: Top 8 Reasons to Eat Them. U.S. FDA Broadens Indication for Verzenio (abemaciclib) in HR+, HER2 [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. I do not believe in random events, of nature or otherwise. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . In comparison, 62.4% of female and 37% of male . They also noted that oxidative stress is one of the causes of chronic diseases and cancer. Asesora y Consultora Web3 para empresas. [13] Hollowell JG, Staehling NW, Flanders WD. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3'-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. It may not display this or other websites correctly. I have so much to say about this I could write a book. BUT, this is the first I have heard of the potential risk of lung cancer in those who take Synthyroid. millions treated for hypothyroidism at risk for lung cancer Treating Elderly for Subclinical Hypothyroidism Can Boost Mortality Rates Iodine - and the lack of it - is implicated in breast cancer, after all. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. In the United States, autoimmune thyroid disease (Hashimoto thyroiditis) is the most common cause of hypothyroidism, but globally lack of iodine in the diet is the most common cause. There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a TSH suppressor. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic self-fulfilling prophecy if you will. Physician/Author on Facebook. millions treated for hypothyroidism at risk for lung cancer END TIME NEWS, A CALL FOR REPENTANCE, YESHUA THE ONLY WAY TO HEAVEN. Obesity epidemic caused by EMF exposures in the ho War on Health - The FDA's Cult of Tyranny. Millions Treated for Hypothyroidism at Risk for Lung Cancer Military veterans face increased risk of HPV-related cancer due to low Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. Angiology 2000, 51:S65S68. Garlic Beats Drug in Detoxifying Lead Safely From How Yoga and Acupuncture Enhance HealthNew Resear Health Nuts: Seeds And Nuts You Should Eat Every Day. I honestly do not know. The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. View the data on GreenMedInfos Hypothyroidism Research page. Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. Objectives: To examine site-specific cancer incidence and mortality and to evaluate the radiation dose-response association after RAI treatment for hyperthyroidism. But what can be done for patients who are at low [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid. J Exp Biol 2010, 213:28992911. Forgot account? If You Don't Want Older Bones, Don't Be Low In Vit Background Mortality Rate for Vaccines, or Pseudo Everything You Ever Wanted to Know About Black Seeds. I very much appreciate the information you shared. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. Another recently approved drug is tepotinib (Tepmetko). J Endocrinol Invest. With the recent announcement by a National Cancer Institute commissioned expert panel that a variety of so-called 'indolent' neoplasms such as ductal carcinoma in situ (DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new disease case the patient is converted into a lifelong customer. [14] K A Woeber. My Endocrinologist was, and continues to be, open about the elevated risk for thyroid cancer due to the multiple. Data sources: The Medline and Cochrane Library electronic databases . Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. This relatively symptom-free reservoir of hypothyroid cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. Gestionar el consentimiento de las cookies. [5]Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5 deiodinase in lung cancer with peripheral lung tissues. Importance: Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase cancer risk remains a controversial issue in medicine and public health. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be.". Acta Endocrinol 1988, 118:460464. Endocrinol. Targeted therapy for lung cancer: Side effects and more Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. Or, simply look at what the young-adult, T-score based definition of osteoporosis and osteopenia has done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. It is very tormenting (for me anyhow) to not know why I got this disease. Untreated hypothyroidism increases morbidity and mortality. I have so many women friends and family members who have recently been diagnosed with hypothyroidism and their doctors put them all on Synthyroid. Researchers are currently studying. [4], More recently DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. Non-ASPS articles which could be relevant. As a person with Graves Disease, I underwent 6 cycles of radio-ablation using i 131 to 'fry' my thyroid gland as surgery was deemed too risky due to the vascularity and size of my gland. Levothyroxine and cancer risk study : Hi sorry to - Thyroid UK Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. Here members can share stories, find important information and learn from the experiences of others like themselves. Monaldi Arch Chest Dis 2003, 59:140145. I think part of sharing information here on Inspire is the discussions about the articles we share. (31) 3351-3382 | 3351-3272 | 3351-3141 | 3351-3371. location of blind frog ranch associe-se. J Exp Biol 2010, 213:28992911. I discovered this article published in Wakeup World. Thyroid dysfunction after immune checkpoint inhibitor treatment in a single-center Chinese cohort: a retrospective study They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. Perhaps she and I could co-author? Scan this QR code to download the app now. Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as "hypothyroidism"? Brit Med J 1978, 1:210212. In 2011 I switched docs and was put on Armour as he told me Synthroid and the like are poison and they do not work. However, they pointed out that the opposite was actually described, and that hypothyroidism reduces the aggressiveness of some cancers because of the presence of thyroid hormone receptors on cancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness of cancers.[1]. 2 Hypothyroidism is the most common type of thyroid disorder, and women's risk of hypothyroidism is five to eight times higher than that of . This discussion has been closed to comments. Just go on one of the thyroid sites and read the stories. Now, I will bring it to the attention of my Endocrinologist. Just another excuse for keeping us on doses that are too low. However, they pointed out that the opposite was recently described, and that "hypothyroidism reduces theaggressiveness of some cancers because of the presence of thyroid hormone receptors oncancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness ofcancers."[1]. rocket fuel, pesticides, fluoride, which induce low thyroid function. As a never smoker I truly wish I smoked so I could just say that's why I got this. Join the Patient & Caregiver Network. This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. See more of Keri Topouzian, D.O. Nanosized aluminum being sprayed in the atmosphere CDC Admits as Many as 30 Million Americans Could b Why Turmeric May Be the Diseased Liver's Best Friend. Metab.87 (2): 48999. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. Brit Med J 1978, 1:210212. I have sent the link that I read today. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)", International Journal of Human Nutrition and Functional Medicine, Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency, 6 Bodily Tissues That Can Be Regenerated Through Nutrition, 7 Simple Ways to Unclog Your Arteries Naturally, Herbal Cream Clears 87.7% of HPV Cases Naturally, How WHOLE Turmeric Heals the Damaged Brain. Non-small cell lung cancer is the most common type of lung cancer, accounting for about 81% of all cases. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. Based just on this article, I think the study's conclusion that Synthroid may cause an increase in lung cancer risk is premature. But that's just me. Intuition and Trust: a Personal Journey Through Ancient Pathways, Meditation, Yoga, Grounding & Mindfulness, Levothyroxine and lung cancer in females: the importance of oxidative stress, 2013 announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs, Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). Are you sure you want to block this member? [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. Compression of the trachea, which may be positional, can occur with nodular goiters and thyroid cancer, and the latter can metastasize to the lungs. J Clin Endocrinol Metab. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: "[I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. What I am personally saying issince I personally have a disease that may kill me, I sure as heck have every right to find out ALL I can about it. Kelly Mellott LinkedIn: Nodify Lung: Nodule Risk Assessment | Biodesix [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. I have always found this condition a riddle. Subclinical hypothyroidism: When to treat | Cleveland Clinic Journal of I bet in the previous discussion, if there was one, we would have concluded it was likely that it was because people are generally not put on enough levothyroxine. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Sin un requerimiento, el cumplimiento voluntario por parte de tu Proveedor de servicios de Internet, o los registros adicionales de un tercero, la informacin almacenada o recuperada slo para este propsito no se puede utilizar para identificarte. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. The American Lung Association connects patients, families, friends and caregivers for support and inspiration as they face lung cancer. Cancer Risk After Radioactive Iodine Treatment for - PubMed The Flu Propaganda Matrix Continues To Promote Fea B Vitamins Slow Alzheimer's and Grey Matter Loss. [13] Hollowell JG, Staehling NW, Flanders WD, et al. In the U.S., the overall five-year survival rate for patients diagnosed with lung cancer is 25%, which is a 21% improvement over the . She wrote about a product called Thyrtophin PMG. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). They only reappear when I need to fine tune the medication. Increased sleepiness. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. It is worth reading. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. [learn more: Is Drug-Based Medicine a Form of Human Sacrifice?] Hashimoto's disease progresses slowly over the years. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer at Symptoms. In my opinion, the science of the study doesn't support the conclusion. In an attempt to show causation, the article notes "patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the "low thyroid," why call chemical poisoning "hypothyroidism"? Baked or Fried avocado fries [Vegetarian]. Salt, Sugar, Fat: 15 Shocking Facts From the Book Dear Doctor, Do You Really Know What Vaccines Cont Colloidal Gold: Discover the Benefits and Wonders, Scientists Explain Why HPV Vaccines Are Unsafe. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". Savvy Senior: Could you have a thyroid problem and not even know it? UpToDate A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. florence nightingale concept 2 via de boleto Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer.